Disease Overview
The Impact of Heart Failure

Understanding Heart Failure


In patients with heart failure, the heart is unable to keep up with its workload, depriving the body of the oxygen it needs to properly function. Patients with advanced heart failure may be oxygen-deprived even at rest.


heart failure:
De-oxygenated blood backs up in the heart


Left-sided heart failure: Failure to properly pump oxygenated blood to the body


Congestive heart failure: Fluid backs up in the heart and pulmonary artery which leads to increasing pressure and fluid in the lungs

Diagnosing Heart Failure

Signs and symptoms of heart failure are not always easy to detect. Doctors assess family history and
personal habits along with medical history and test results to understand the severity of heart failure.

Assessment of Patient Symptoms New York Heart Association (NYHA) Functional Classification

Class I No limitations of activity
Class II Minor limitations of activity.
Class III Significant limitations of activity.
Class IV Unable to perform normal activities.

Clinical Evaluation ACC/AHA Heart Failure Classification

Stage A No evidence of cardiovascular disease. No symptoms.
Stage B Minimal cardiovascular disease. Mild symptoms.
Stage C Moderately severe cardiovascular disease. Significant limitations.
Stage D Severe cardiovascular disease. Unable to perform normal activities.

Current Treatment
Treating Heart Failure

Heart failure is a complex disease, and patients are often treated using one or more therapies. These therapies aim to improve a patient's quality of life and slow progression of the disease.

Healthy Lifestyle Changes
  • Quit smoking
  • Maintain a healthy weight
  • Monitor daily fluid and salt intake
  • Be active
  • Monitor symptoms
Cardiac Rehab
  • Medically supervised program with counseling and support to improve heart health
  • Improve the heart’s ability to pump
  • Prevent fluid build-up
  • Improve blood flow
Devices and Surgical Procedures
  • Implantable Cardioverter – Defibrillator (ICD)
  • Cardiac Resynchronization Therapy (CRT)
  • Valve repair
  • Left Ventricular Assist Device (LVAD)
  • Heart transplant

Challenges in Managing Advanced Heart Failure

Poor Patient Outcomes

Despite 20 years of advancement in treating heart failure and well-established guidelines, patient outcomes remain poor.


Successful treatment requires patient involvement, however many patients and caregivers feel isolated and overwhelmed.


Outpatient management of complex patients with acute needs creates a cycle of reactive care which leads to inefficiencies in care management.

Learn more about the CordellaTM Heart Failure System

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1 Ponikowski P et al. Heart failure: preventing disease and death worldwide. ESC Heart Failure 2015;1:4–25.
2 American Heart Association (AHA) http://www.heart.org/HEARTORG/Conditions/HeartFailure/LivingWithHeartFailureAndAdvancedHF/Advanced-Heart-Failure_UCM_441925_Article.jsp#.WA-jsjKZNR0 Accessed. 10/25/16
3 Heidenreich PA, et al. Forecasting the Impact of Heart Failure in the U.S. Circ Heart Fail. 2013 May; 6(3): 606–619