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Disease Overview
The Impact of Heart Failure


Understanding Heart Failure

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In patients with heart failure, the heart is unable to keep up with its workload. The body is deprived of the oxygen it needs to properly function and some patients may feel symptomatic even at rest.

a

Right-sided
heart failure:
De-oxygenated blood backs up in the heart

b

Left-sided heart failure: Failure to properly pump oxygenated blood to the body

c

Congestive heart failure: Fluid backs up in the heart and pulmonary artery which leads to increasing pressure and fluid in the lungs

Diagnosing Heart Failure

Signs and symptoms of heart failure are not always easy to detect. Doctors assess family history and
personal habits along with medical history and test results to understand the severity of heart failure.

Assessment of Patient Symptoms New York Heart Association (NYHA) Functional Classification

Class I No limitations of activity.
Class II Minor limitations of activity.
Class III Significant limitations of activity.
Class IV Unable to perform normal activities.
 

Clinical Evaluation ACC/AHA Heart Failure Classification

Stage A No evidence of cardiovascular disease. No symptoms.
Stage B Minimal cardiovascular disease. Mild symptoms.
Stage C Moderately severe cardiovascular disease. Significant limitations.
Stage D Severe cardiovascular disease. Unable to perform normal activities.

Current Treatment
Treating Heart Failure

Heart failure is a complex disease, and patients are often treated using one or more therapies. These therapies aim to improve a patient's quality of life and slow progression of the disease.

Healthy Lifestyle Changes
  • Quit smoking
  • Maintain a healthy weight
  • Monitor daily fluid and salt intake
  • Be active
Cardiac Rehab
  • Medically supervised program with counseling and support to improve heart health
Medications
  • Improve the heart’s ability to pump
  • Prevent fluid build-up
  • Improve blood flow
Medical Devices and Procedures
  • Implantable Cardioverter Defibrillator (ICD)
  • Cardiac Resynchronization Therapy (CRT)
  • Pulmonary Artery (PA) Pressure Sensor
  • Valve repair
  • Left Ventricular Assist Device (LVAD)
  • Heart transplant

Challenges
Challenges in Managing Heart Failure

Poor Patient Outcomes

Despite advancements in treating heart failure and well-established guidelines, patient outcomes remain poor.

LOW PATIENT INVOLVEMENT

Many patients and caregivers feel isolated and overwhelmed, creating a disconnection that impacts outcomes.

COMPLEX CARE MANAGEMENT

Complex patients and care management inefficiencies result in medication dosing that is not optimized and a reactive cycle of care.

Cordella™ Can Help

Endotronix is improving heart failure care in the home.

Additional information about heart failure

1 Ponikowski P et al. Heart failure: preventing disease and death worldwide. ESC Heart Failure 2015;1:4–25.
2 American Heart Association (AHA)
http://www.heart.org/HEARTORG/Conditions/HeartFailure/LivingWithHeartFailureAndAdvancedHF/Advanced-Heart-Failure_UCM_441925_Article.jsp#.WA-jsjKZNR0 Accessed. 10/25/16
3 Heidenreich PA, et al. Forecasting the Impact of Heart Failure in the U.S. Circ Heart Fail. 2013 May; 6(3): 606–619
The Cordella™ PA Pressure Sensor System is an investigational device and is not currently approved for clinical use in any geography.
CAUTION – Investigational Device. Limited by Federal (or United States) Law to Investigational Use.
Exclusively for Clinical Investigation.

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